Description
Product Characteristics: This gene encodes a basic helix-loop-helix protein expressed in various tissues. The encoded protein can interact with ARNTL or compete for E-box binding sites in the promoter of PER1 and repress CLOCK/ARNTL's transactivation of PER1. This gene is believed to be involved in the control of circadian rhythm and cell differentiation. Defects in this gene are associated with the short sleep phenotype.,BHLHE41,BHLHB3,DEC2,SHARP1,hDEC2,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,Endocrine & Metabolism,Neuroscience,BHLHE41
Target Information: This gene encodes a transcription factor that belongs to the Hairy/Enhancer of Split subfamily of basic helix-loop-helix factors. The encoded protein functions as a transcriptional repressor and as a regulator of molecular clock. Defects in this gene are associated with the short sleep phenotype. [provided by RefSeq, May 2010]